Combining Urinary Detection of TMPRSS2:ERG and PCA3 with Serum PSA to Predict Diagnosis of Prostate Cancer

OBJECTIVES: We sought to develop a clinical algorithm combining serum PSA with detection of TMPRSS2:ERG fusion and PCA3 in urine collected after digital rectal exam (post-DRE urine) to predict prostate cancer on subsequent biopsy. MATERIALS AND METHODS: Post-DRE urine was collected in 48 consecutive...

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Main Authors: Salami, Simpa S., Schmidt, Folke, Laxman, Bharathi, Regan, Meredith M., Rickman, David S., Scherr, Douglas, Bueti, Gerardina, Siddiqui, Javed, Tomlins, Scott A., Wei, John T., Chinnaiyan, Arul, Rubin, Mark A., Sanda, Martin G.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210917/
https://ncbi.nlm.nih.gov/pubmed/21600800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.urolonc.2011.04.001
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