Pulmonary Response to Surface-Coated Nanotitanium Dioxide Particles Includes Induction of Acute Phase Response Genes, Inflammatory Cascades, and Changes in MicroRNAs: A Toxicogenomic Study

Titanium dioxide nanoparticles (nanoTiO(2)) are used in various applications including in paints. NanoTiO(2) inhalation may induce pulmonary toxicity and systemic effects. However, the underlying molecular mechanisms are poorly understood. In this study, the effects of inhaled surface-coated nanoTiO...

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Detalhes bibliográficos
Main Authors: Halappanavar, Sabina, Jackson, Petra, Williams, Andrew, Jensen, Keld A, Hougaard, Karin S, Vogel, Ulla, Yauk, Carole L, Wallin, Håkan
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210826/
https://ncbi.nlm.nih.gov/pubmed/21259345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20639
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