Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis

Global pulmonary and hepatic messenger RNA profiles in adult female C57BL/6 mice intratracheally instilled with carbon black nanoparticles (NPs) (Printex 90) were analyzed to identify biological perturbations underlying systemic responses to NP exposure. Tissue gene expression changes were profiled...

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Detalhes bibliográficos
Main Authors: Bourdon, Julie A., Halappanavar, Sabina, Saber, Anne T., Jacobsen, Nicklas R., Williams, Andrew, Wallin, Håkan, Vogel, Ulla, Yauk, Carole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Nanotoxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355316/
https://ncbi.nlm.nih.gov/pubmed/22461453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs119
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