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A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development

The phosphatidylinositol 3-kinase (PI3K) signaling pathway is a conserved signal transduction cascade that is fundamental for the correct development of the nervous system. The major negative regulator of PI3K signaling is the lipid phosphatase DAF-18/PTEN, which can modulate PI3K pathway activity d...

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Autors principals: Christensen, Ryan, de la Torre-Ubieta, Luis, Bonni, Azad, Colón-Ramos, Daniel A.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210501/
https://ncbi.nlm.nih.gov/pubmed/22069193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.069062
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