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Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries

The accumulation of small strokes has been linked to cognitive dysfunction. Although most animal models have focused on the impact of arteriole occlusions, clinical evidence indicates that venule occlusions may also be important. We used two-photon excited fluorescence microscopy to quantify changes...

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Autori principali: Nguyen, John, Nishimura, Nozomi, Fetcho, Robert N, Iadecola, Costantino, Schaffer, Chris B
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210348/
https://ncbi.nlm.nih.gov/pubmed/21712834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.95
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