8-Modified-2′-Deoxyadenosine Analogues Induce Delayed Polymerization Arrest during HIV-1 Reverse Transcription

The occurrence of resistant viruses to any of the anti-HIV-1 compounds used in the current therapies against AIDS underlies the urge for the development of new drug targets and/or new drugs acting through novel mechanisms. While all anti-HIV-1 nucleoside analogues in clinical use and in clinical tri...

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Autores principales: Vivet-Boudou, Valérie, Isel, Catherine, Sleiman, Marwan, Smyth, Redmond, Ben Gaied, Nouha, Barhoum, Patrick, Laumond, Géraldine, Bec, Guillaume, Götte, Matthias, Mak, Johnson, Aubertin, Anne-Marie, Burger, Alain, Marquet, Roland
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210175/
https://ncbi.nlm.nih.gov/pubmed/22087320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027456
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