The Antiangiogenic 16K Prolactin Impairs Functional Tumor Neovascularization by Inhibiting Vessel Maturation

BACKGROUND: Angiogenesis, the formation of new blood vessels from existing vasculature, plays an essential role in tumor growth, invasion, and metastasis. 16K hPRL, the antiangiogenic 16-kDa N-terminal fragment of human prolactin was shown to prevent tumor growth and metastasis by modifying tumor ve...

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Detalhes bibliográficos
Main Authors: Nguyen, Ngoc-Quynh-Nhu, Castermans, Karolien, Berndt, Sarah, Herkenne, Stephanie, Tabruyn, Sebastien P., Blacher, Silvia, Lion, Michelle, Noel, Agnes, Martial, Joseph A., Struman, Ingrid
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210157/
https://ncbi.nlm.nih.gov/pubmed/22087289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027318
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