MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16-kDa N-terminal prolactin fragment (16K PRL), the underlying molecular mechanisms are poorly understood. We found that 16K PRL induced micr...

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Autores principales: Halkein, Julie, Tabruyn, Sebastien P., Ricke-Hoch, Melanie, Haghikia, Arash, Nguyen, Ngoc-Quynh-Nhu, Scherr, Michaela, Castermans, Karolien, Malvaux, Ludovic, Lambert, Vincent, Thiry, Marc, Sliwa, Karen, Noel, Agnes, Martial, Joseph A., Hilfiker-Kleiner, Denise, Struman, Ingrid
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638905/
https://ncbi.nlm.nih.gov/pubmed/23619365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI64365
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