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Improving the Estimation of Celiac Disease Sibling Risk by Non-HLA Genes

Celiac Disease (CD) is a polygenic trait, and HLA genes explain less than half of the genetic variation. Through large GWAs more than 40 associated non-HLA genes were identified, but they give a small contribution to the heritability of the disease. The aim of this study is to improve the estimate o...

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Bibliografski detalji
Glavni autori: Izzo, Valentina, Pinelli, Michele, Tinto, Nadia, Esposito, Maria Valeria, Cola, Arturo, Sperandeo, Maria Pia, Tucci, Francesca, Cocozza, Sergio, Greco, Luigi, Sacchetti, Lucia
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210127/
https://ncbi.nlm.nih.gov/pubmed/22087237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026920
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