IL28B rs12979860 Genotype and Spontaneous Clearance of Hepatitis C Virus in a Multi-Ethnic Cohort of Injection Drug Users: Evidence for a Supra-Additive Association

Among 1369 Urban Health Study participants, we evaluated genetic models for the association of IL28B genotype (rs12979860 and rs8099917) with hepatitis C virus (HCV) clearance. For rs12979860, adjusted odds ratios for spontaneous HCV clearance were as follows: IL28B-CC, 3.88 (P < .001); IL28B-CT,...

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Hlavní autoři: Shebl, Fatma M., Pfeiffer, Ruth M., Buckett, Dianna, Muchmore, Brian, Chen, Sabrina, Dotrang, Myhanh, Prokunina-Olsson, Ludmila, Edlin, Brian R., O’Brien, Thomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209810/
https://ncbi.nlm.nih.gov/pubmed/22013224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir647
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