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Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-sensitive Domain Changes in Differentiated Neurons

Although unnatural amino acids (Uaas) have been genetically encoded in bacterial, fungal and mammalian cells using orthogonal tRNA/aminoacyl-tRNA synthetase pairs, applications of this method to a wider range of specialized cell types, such as stem cells, still face challenges. While relatively stra...

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Autors principals: Shen, Bin, Xiang, Zheng, Miller, Barbara, Louie, Gordon, Wang, Wenyuan, Noel, Joseph P., Gage, Fred H., Wang, Lei
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209808/
https://ncbi.nlm.nih.gov/pubmed/21681861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.679
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