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Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein
Proteins attain their function only after folding into a highly organized three-dimensional structure. Much remains to be learned about the mechanisms of folding of large multidomain proteins, which may populate metastable intermediate states on their energy landscapes. Here we introduce a novel met...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209527/ https://ncbi.nlm.nih.gov/pubmed/21988909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1504 |
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