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Single-molecule fluorescence spectroscopy maps the folding landscape of a large protein

Proteins attain their function only after folding into a highly organized three-dimensional structure. Much remains to be learned about the mechanisms of folding of large multidomain proteins, which may populate metastable intermediate states on their energy landscapes. Here we introduce a novel met...

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Detalles Bibliográficos
Main Authors: Pirchi, Menahem, Ziv, Guy, Riven, Inbal, Cohen, Sharona Sedghani, Zohar, Nir, Barak, Yoav, Haran, Gilad
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209527/
https://ncbi.nlm.nih.gov/pubmed/21988909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1504
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