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Mechanistic analysis of local ori melting and helicase assembly by the papillomavirus E1 protein

Preparation of DNA templates for replication requires opening of the duplex to expose single stranded (ss) DNA. The locally melted DNA is required for replicative DNA helicases to initiate unwinding. How local melting is generated in eukaryotic replicons is unknown, but initiator proteins from a han...

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Bibliografske podrobnosti
Main Authors: Schuck, Stephen, Stenlund, Arne
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209524/
https://ncbi.nlm.nih.gov/pubmed/21884978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.026
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