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Mechanistic analysis of local ori melting and helicase assembly by the papillomavirus E1 protein

Preparation of DNA templates for replication requires opening of the duplex to expose single stranded (ss) DNA. The locally melted DNA is required for replicative DNA helicases to initiate unwinding. How local melting is generated in eukaryotic replicons is unknown, but initiator proteins from a han...

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Detalles Bibliográficos
Main Authors: Schuck, Stephen, Stenlund, Arne
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209524/
https://ncbi.nlm.nih.gov/pubmed/21884978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.026
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