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Structure-Based Mutational Analysis of the Bovine Papillomavirus E1 Helicase Domain Identifies Residues Involved in the Nonspecific DNA Binding Activity Required for Double Trimer Formation

The papillomavirus E1 protein is a multifunctional initiator protein responsible for preparing the viral DNA template for initiation of DNA replication. The E1 protein encodes two DNA binding activities that are required for initiation of DNA replication. A well-characterized sequence-specific DNA b...

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Bibliografiske detaljer
Main Authors: Liu, Xiaofei, Schuck, Stephen, Stenlund, Arne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863750/
https://ncbi.nlm.nih.gov/pubmed/20147403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02214-09
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