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The novel trisubstituted pyran derivative D-142 has triple monoamine reuptake inhibitory activity and exerts potent antidepressant-like activity in rodents

Major depression disorder is a significant health problem with 10-20% of all adults suffering from this disease. The underlying causes of depression are still unclear and 15% of depressed patients are resistant to all known therapies. Monoamine therapies have so far been the most successful approach...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Dutta, Aloke K., Gopishetty, Bhaskar, Gogoi, Sanjib, Ali, Solav, Zhen, Juan, Reith, Maarten
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209502/
https://ncbi.nlm.nih.gov/pubmed/21963455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.09.162
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