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Crystallographic Trapping of Heme Loss Intermediates During the Nitrite-Induced Degradation of Human Hemoglobin

Heme is an important cofactor in a large number of essential proteins and is often involved in small molecule binding and activation. Heme loss from proteins thus negatively affects the function of these proteins, but is also an important component of iron recycling. The characterization of intermed...

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Detalhes bibliográficos
Main Authors: Yi, Jun, Thomas, Leonard M., Musayev, Faik N., Safo, Martin K., Richter-Addo, George B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209482/
https://ncbi.nlm.nih.gov/pubmed/21863786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2009322
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