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The Cellular TAR RNA Binding Protein, TRBP, Promotes HIV-1 Replication Primarily by Inhibiting the Activation of Double-Stranded RNA-Dependent Kinase PKR

The TAR RNA binding protein, TRBP, is a cellular double-stranded RNA (dsRNA) binding protein that can promote the replication of HIV-1 through interactions with the viral TAR element as well as with cellular proteins that affect the efficiency of translation of viral transcripts. The structured TAR...

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Detalhes bibliográficos
Main Authors: Sanghvi, Viraj R., Steel, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209364/
https://ncbi.nlm.nih.gov/pubmed/21937648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05240-11
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