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A Genetic Interaction between the Core and NS3 Proteins of Hepatitis C Virus Is Essential for Production of Infectious Virus

By analogy to other members of the Flaviviridae family, the hepatitis C virus (HCV) core protein is presumed to oligomerize to form the viral nucleocapsid, which encloses the single-stranded RNA genome. Core protein is directed to lipid droplets (LDs) by domain 2 (D2) of the protein, and this proces...

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Detalhes bibliográficos
Main Authors: Jones, Daniel M., Atoom, Ali M., Zhang, Xiaozhen, Kottilil, Shyamasundaran, Russell, Rodney S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209351/
https://ncbi.nlm.nih.gov/pubmed/21957313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05313-11
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