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Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein

The hepatitis C virus (HCV) NS2 protein has dual roles within the HCV life cycle. While well characterized as an autoprotease that cleaves the NS2/NS3 junction, NS2, primarily via its N-terminal region, is also involved in virion morphogenesis. In order to map the determinants necessary for infectio...

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Autors principals: de la Fuente, Cynthia, Goodman, Zachary, Rice, Charles M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624385/
https://ncbi.nlm.nih.gov/pubmed/23408609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03174-12
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