ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells

HIV-1-infected cells are partially resistant to anti-HIV cytotoxic T lymphocytes (CTLs) due to the effects of the HIV Nef protein on antigen presentation by major histocompatibility complex class I (MHC-I), and evidence has been accumulating that this function of Nef is important in vivo. HIV Nef di...

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Detalhes bibliográficos
Main Authors: Wonderlich, Elizabeth R., Leonard, Jolie A., Kulpa, Deanna A., Leopold, Kay E., Norman, Jason M., Collins, Kathleen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209341/
https://ncbi.nlm.nih.gov/pubmed/21917951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00056-11
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