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Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation

Defining the mechanisms of chromosomal cohesion and dissolution of the cohesin complex from chromatids is important for understanding the chromosomal missegregation seen in many tumor cells. Here we report the identification of a novel cohesin-resolving protease and describe its role in chromosomal...

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Detalhes bibliográficos
Main Authors: Panigrahi, Anil K., Zhang, Nenggang, Mao, Qilong, Pati, Debananda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209327/
https://ncbi.nlm.nih.gov/pubmed/21876002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06075-11
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