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Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation

Defining the mechanisms of chromosomal cohesion and dissolution of the cohesin complex from chromatids is important for understanding the chromosomal missegregation seen in many tumor cells. Here we report the identification of a novel cohesin-resolving protease and describe its role in chromosomal...

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Main Authors: Panigrahi, Anil K., Zhang, Nenggang, Mao, Qilong, Pati, Debananda
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209327/
https://ncbi.nlm.nih.gov/pubmed/21876002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06075-11
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