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Calpain-1 Cleaves Rad21 To Promote Sister Chromatid Separation
Defining the mechanisms of chromosomal cohesion and dissolution of the cohesin complex from chromatids is important for understanding the chromosomal missegregation seen in many tumor cells. Here we report the identification of a novel cohesin-resolving protease and describe its role in chromosomal...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209327/ https://ncbi.nlm.nih.gov/pubmed/21876002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.06075-11 |
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