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Linking Sister Chromatid Cohesion and Apoptosis: Role of Rad21

Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspase-like enzyme, allows chromosomal separation. We show that cleavage of human Rad21 (hRad21) also occurs during apoptosis induced by diverse stimuli. Inducti...

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Detalhes bibliográficos
Main Authors: Pati, Debananda, Zhang, Nenggang, Plon, Sharon E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134054/
https://ncbi.nlm.nih.gov/pubmed/12417729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8267-8277.2002
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