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Gab2 Promotes Colony-Stimulating Factor 1-Regulated Macrophage Expansion via Alternate Effectors at Different Stages of Development

Colony-stimulating factor 1 (CSF-1) receptor (CSF-1R, or macrophage CSF receptor [M-CSFR]) is the primary regulator of the proliferation, survival, and differentiation of mononuclear phagocytes (MNPs), but the critical CSF-1 signals for these functions are unclear. The scaffold protein Gab2 is a maj...

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Detalhes bibliográficos
Main Authors: Lee, Angel W., Mao, Yingwei, Penninger, Josef M., Yu, Soojie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209260/
https://ncbi.nlm.nih.gov/pubmed/21930791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05706-11
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