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SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling
Formation of the immunological synapse between an antigen-presenting cell (APC) and a T cell leads to signal generation in both cells involved. In T cells, the lipid raft-associated transmembrane adaptor protein LAT plays a central role. Its phosphorylation is a crucial step in signal propagation, i...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3209250/ https://ncbi.nlm.nih.gov/pubmed/21930792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05817-11 |
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