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SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling

Formation of the immunological synapse between an antigen-presenting cell (APC) and a T cell leads to signal generation in both cells involved. In T cells, the lipid raft-associated transmembrane adaptor protein LAT plays a central role. Its phosphorylation is a crucial step in signal propagation, i...

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Autors principals: Draber, Peter, Vonkova, Ivana, Stepanek, Ondrej, Hrdinka, Matous, Kucova, Marketa, Skopcova, Tereza, Otahal, Pavel, Angelisova, Pavla, Horejsi, Vaclav, Yeung, Mandy, Weiss, Arthur, Brdicka, Tomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209250/
https://ncbi.nlm.nih.gov/pubmed/21930792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05817-11
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