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PRION-1 scales analysis supports use of functional outcome measures in prion disease
OBJECTIVES: Human prion diseases are heterogeneous but invariably fatal neurodegenerative disorders with no known effective therapy. PRION-1, the largest clinical trial in prion disease to date, showed no effect of the potential therapeutic quinacrine on survival. Although there are several limitati...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208955/ https://ncbi.nlm.nih.gov/pubmed/22013183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182364890 |
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