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Thermodynamic Analysis of Protein-Ligand Interactions in Complex Biological Mixtures using a Shotgun Proteomics Approach
Shotgun proteomics protocols are widely used for the identification and/or quantitation of proteins in complex biological samples. Described here is a shotgun proteomics protocol that can be used to identify the protein targets of biologically relevant ligands in complex protein mixtures. The protoc...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208786/ https://ncbi.nlm.nih.gov/pubmed/21905665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200403c |
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