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Thermodynamic Analysis of Protein-Ligand Interactions in Complex Biological Mixtures using a Shotgun Proteomics Approach

Shotgun proteomics protocols are widely used for the identification and/or quantitation of proteins in complex biological samples. Described here is a shotgun proteomics protocol that can be used to identify the protein targets of biologically relevant ligands in complex protein mixtures. The protoc...

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Bibliographic Details
Main Authors: DeArmond, Patrick D., Xu, Ying, Strickland, Erin C., Daniels, Kyle G., Fitzgerald, Michael C.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208786/
https://ncbi.nlm.nih.gov/pubmed/21905665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200403c
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