Mutation analysis of the tyrosine phosphatase PTPN2 in Hodgkin’s lymphoma and T-cell non-Hodgkin’s lymphoma

We recently reported deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia. Functional analyses confirmed that PTPN2 acts as classical tumor suppressor repressing the proliferation of T cells, in part through inhibition of JAK/STAT signaling. We investigated...

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Bibliografski detalji
Glavni autori: Kleppe, Maria, Tousseyn, Thomas, Geissinger, Eva, Kalender Atak, Zeynep, Aerts, Stein, Rosenwald, Andreas, Wlodarska, Iwona, Cools, Jan
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2011
Teme:
Brief Reports
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208694/
https://ncbi.nlm.nih.gov/pubmed/21791476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.041921
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