Inner ear dysfunction in caspase-3 deficient mice

BACKGROUND: Caspase-3 is one of the most downstream enzymes activated in the apoptotic pathway. In caspase-3 deficient mice, loss of cochlear hair cells and spiral ganglion cells coincide closely with hearing loss. In contrast with the auditory system, details of the vestibular phenotype have not be...

Full description

Saved in:
Bibliographic Details
Main Authors: Makishima, Tomoko, Hochman, Lara, Armstrong, Patrick, Rosenberger, Eric, Ridley, Ryan, Woo, Minna, Perachio, Adrian, Wood, Scott
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208590/
https://ncbi.nlm.nih.gov/pubmed/21988729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-102
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items