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Inner ear dysfunction in caspase-3 deficient mice

BACKGROUND: Caspase-3 is one of the most downstream enzymes activated in the apoptotic pathway. In caspase-3 deficient mice, loss of cochlear hair cells and spiral ganglion cells coincide closely with hearing loss. In contrast with the auditory system, details of the vestibular phenotype have not be...

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Detalhes bibliográficos
Main Authors: Makishima, Tomoko, Hochman, Lara, Armstrong, Patrick, Rosenberger, Eric, Ridley, Ryan, Woo, Minna, Perachio, Adrian, Wood, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208590/
https://ncbi.nlm.nih.gov/pubmed/21988729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-102
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