Modeling the Mechanism of Action of a DGAT1 Inhibitor Using a Causal Reasoning Platform

Triglyceride accumulation is associated with obesity and type 2 diabetes. Genetic disruption of diacylglycerol acyltransferase 1 (DGAT1), which catalyzes the final reaction of triglyceride synthesis, confers dramatic resistance to high-fat diet induced obesity. Hence, DGAT1 is considered a potential...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Enayetallah, Ahmed E., Ziemek, Daniel, Leininger, Michael T., Randhawa, Ranjit, Yang, Jianxin, Manion, Tara B., Mather, Dawn E., Zavadoski, William J., Kuhn, Max, Treadway, Judith L., des Etages, Shelly Ann G., Gibbs, E. Michael, Greene, Nigel, Steppan, Claire M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208573/
https://ncbi.nlm.nih.gov/pubmed/22073239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027009
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker