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Hyaluronan Signaling during Ozone-Induced Lung Injury Requires TLR4, MyD88, and TIRAP

Ozone exposure is associated with exacerbation of reactive airways disease. We have previously reported that the damage-associated molecular pattern, hyaluronan, is required for the complete biological response to ambient ozone and that hyaluronan fragments signal through toll-like receptor 4 (TLR4)...

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Detalles Bibliográficos
Main Authors: Li, Zhuowei, Potts-Kant, Erin N., Garantziotis, Stavros, Foster, W. Michael, Hollingsworth, John W.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208559/
https://ncbi.nlm.nih.gov/pubmed/22073274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027137
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