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Context Mediates Antimicrobial Efficacy of Kinocidin Congener Peptide RP-1

Structure-mechanism relationships are key determinants of host defense peptide efficacy. These relationships are influenced by anatomic, physiologic and microbiologic contexts. Structure-mechanism correlates were assessed for the synthetic peptide RP-1, modeled on microbicidal domains of platelet ki...

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Detalhes bibliográficos
Main Authors: Yount, Nannette Y., Cohen, Samuel E., Kupferwasser, Deborah, Waring, Alan J., Ruchala, Piotr, Sharma, Shantanu, Wasserman, Karlman, Jung, Chun-Ling, Yeaman, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208557/
https://ncbi.nlm.nih.gov/pubmed/22073187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026727
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