Estrogen Receptor (ESR1) mRNA Expression and Benefit From Tamoxifen in the Treatment and Prevention of Estrogen Receptor–Positive Breast Cancer

PURPOSE: Several mechanisms have been proposed to explain tamoxifen resistance of estrogen receptor (ER) –positive tumors, but a clinically useful explanation for such resistance has not been described. Because the ER is the treatment target for tamoxifen, a linear association between ER expression...

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Autors principals: Kim, Chungyeul, Tang, Gong, Pogue-Geile, Katherine L., Costantino, Joseph P., Baehner, Frederick L., Baker, Joffre, Cronin, Maureen T., Watson, Drew, Shak, Steven, Bohn, Olga L., Fumagalli, Debora, Taniyama, Yusuke, Lee, Ahwon, Reilly, Megan L., Vogel, Victor G., McCaskill-Stevens, Worta, Ford, Leslie G., Geyer, Charles E., Wickerham, D. Lawrence, Wolmark, Norman, Paik, Soonmyung
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2011
Matèries:
Original Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208536/
https://ncbi.nlm.nih.gov/pubmed/21947828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2010.32.9615
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