Src homology domain-containing phosphatase 2 suppresses cellular senescence in glioblastoma

BACKGROUND: Epidermal growth factor receptor (EGFR) signalling is frequently altered during glioblastoma de novo pathogenesis. An important downstream modulator of this signal cascade is SHP2 (Src homology domain-containing phosphatase 2). METHODS: We examined the The Cancer Genome Atlas (TCGA) data...

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Detalles Bibliográficos
Autores principales: Sturla, L-M, Zinn, P O, Ng, K, Nitta, M, Kozono, D, Chen, C C, Kasper, E M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208488/
https://ncbi.nlm.nih.gov/pubmed/21934682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.345
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