Silencing of RhoA nucleotide exchange factor, ARHGEF3, reveals its unexpected role in iron uptake

Genomewide association meta-analysis studies have identified > 100 independent genetic loci associated with blood cell indices, including volume and count of platelets and erythrocytes. Although several of these loci encode known regulators of hematopoiesis, the mechanism by which most sequence v...

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Autors principals: Serbanovic-Canic, Jovana, Cvejic, Ana, Soranzo, Nicole, Stemple, Derek L., Ouwehand, Willem H., Freson, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
Matèries:
Red Cells, Iron, and Erythropoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208301/
https://ncbi.nlm.nih.gov/pubmed/21715309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-337295
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