Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II

Previous studies from our group have demonstrated that bone morphogenetic protein receptor-II (BMPR-II), expressed on pulmonary artery endothelial cells, imparts profound anti-inflammatory effects by regulating the release of proinflammatory cytokines and promoting barrier function by suppressing th...

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Detaylı Bibliyografya
Asıl Yazarlar: Burton, Victoria J., Holmes, Alan M., Ciuclan, Loredana I., Robinson, Alexander, Roger, Jan S., Jarai, Gabor, Pearce, Andrew C., Budd, David C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2011
Konular:
Vascular Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208288/
https://ncbi.nlm.nih.gov/pubmed/21900197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-05-347393
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