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The impact of Fc-γ receptor polymorphisms in elderly patients with diffuse large B-cell lymphoma treated with CHOP with or without rituximab

Fcγ receptor (FcγR) polymorphisms have been shown to affect rituximab-mediated antibody-dependent cellular cytotoxicity. Of 512 patients with diffuse large B-cell lymphoma treated in the RICOVER-60 trial, carriers of FcγRIII 158 valine homozygous receptors (V/V) presented with a slightly decreased i...

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Autori principali: Ahlgrimm, Manfred, Pfreundschuh, Michael, Kreuz, Markus, Regitz, Evi, Preuss, Klaus-Dieter, Bittenbring, Joerg
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208281/
https://ncbi.nlm.nih.gov/pubmed/21900198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-346411
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