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Aldose Reductase Deficiency Protects from Autoimmune- and Endotoxin-Induced Uveitis in Mice
PURPOSE. To investigate the effect of aldose reductase (AR) deficiency in protecting the chronic experimental autoimmune (EAU) and acute endotoxin-induced uveitis (EIU) in c57BL/6 mice. METHODS. The WT and AR-null (ARKO) mice were immunized with human interphotoreceptor retinoid-binding peptide (hIR...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3208006/ https://ncbi.nlm.nih.gov/pubmed/21911582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7830 |
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