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Aldose Reductase Deficiency Protects from Autoimmune- and Endotoxin-Induced Uveitis in Mice

PURPOSE. To investigate the effect of aldose reductase (AR) deficiency in protecting the chronic experimental autoimmune (EAU) and acute endotoxin-induced uveitis (EIU) in c57BL/6 mice. METHODS. The WT and AR-null (ARKO) mice were immunized with human interphotoreceptor retinoid-binding peptide (hIR...

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Autori principali: Yadav, Umesh C. S., Shoeb, Mohammed, Srivastava, Satish K., Ramana, Kota V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Association for Research in Vision and Ophthalmology, Inc. 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208006/
https://ncbi.nlm.nih.gov/pubmed/21911582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7830
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