A genome-wide survey for SNPs altering microRNA seed sites identifies functional candidates in GWAS

BACKGROUND: Gene variants within regulatory regions are thought to be major contributors of the variation of complex traits/diseases. Genome wide association studies (GWAS), have identified scores of genetic variants that appear to contribute to human disease risk. However, most of these variants do...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Richardson, Kris, Lai, Chao-Qiang, Parnell, Laurence D, Lee, Yu-Chi, Ordovas, Jose M
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207998/
https://ncbi.nlm.nih.gov/pubmed/21995669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-504
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