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Anti-filarial Activity of Antibiotic Therapy Is Due to Extensive Apoptosis after Wolbachia Depletion from Filarial Nematodes

Filarial nematodes maintain a mutualistic relationship with the endosymbiont Wolbachia. Depletion of Wolbachia produces profound defects in nematode development, fertility and viability and thus has great promise as a novel approach for treating filarial diseases. However, little is known concerning...

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Bibliographic Details
Main Authors: Landmann, Frederic, Voronin, Denis, Sullivan, William, Taylor, Mark J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207916/
https://ncbi.nlm.nih.gov/pubmed/22072969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002351
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