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Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes

BACKGROUND: Lymphatic filariasis and onchocerciasis are debilitating diseases caused by filarial nematodes. Disease pathogenesis is induced by inflammatory responses following the death of the parasite. Wolbachia endosymbionts of filariae are potent inducers of innate and adaptive inflammation and b...

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Bibliografiske detaljer
Main Authors: Johnston, Kelly L, Wu, Bo, Guimarães, Ana, Ford, Louise, Slatko, Barton E, Taylor, Mark J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964653/
https://ncbi.nlm.nih.gov/pubmed/20946650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-3-99
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