A Novel Protein LZTFL1 Regulates Ciliary Trafficking of the BBSome and Smoothened

Many signaling proteins including G protein-coupled receptors localize to primary cilia, regulating cellular processes including differentiation, proliferation, organogenesis, and tumorigenesis. Bardet-Biedl Syndrome (BBS) proteins are involved in maintaining ciliary function by mediating protein tr...

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Bibliographic Details
Main Authors: Seo, Seongjin, Zhang, Qihong, Bugge, Kevin, Breslow, David K., Searby, Charles C., Nachury, Maxence V., Sheffield, Val C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207910/
https://ncbi.nlm.nih.gov/pubmed/22072986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002358
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