Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

The forkhead transcription factor Foxn1 is indispensable for thymus development, but the mechanisms by which it mediates thymic epithelial cell (TEC) development are poorly understood. To examine the cellular and molecular basis of Foxn1 function, we generated a novel and revertible hypomorphic alle...

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Hauptverfasser: Nowell, Craig S., Bredenkamp, Nicholas, Tetélin, Stéphanie, Jin, Xin, Tischner, Christin, Vaidya, Harsh, Sheridan, Julie M., Stenhouse, Frances Hogg, Heussen, Raphaela, Smith, Andrew J. H., Blackburn, C. Clare
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207875/
https://ncbi.nlm.nih.gov/pubmed/22072979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002348
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