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A Switch from Canonical to Noncanonical Wnt Signaling Mediates Drug Resistance in Colon Cancer Cells

Butyrate, a fermentation product of fiber in the colon, acts as a histone deacetylase inhibitor (HDACi) and induces apoptosis in colon cancer (CC) cells in vitro. We have reported that the apoptotic effects of butyrate are dependent upon the hyperactivation of the Wnt/beta-catenin pathway. However,...

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מידע ביבליוגרפי
Main Authors: Bordonaro, Michael, Tewari, Shruti, Cicco, Catherine E., Atamna, Wafa, Lazarova, Darina L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207861/
https://ncbi.nlm.nih.gov/pubmed/22073312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027308
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