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CXCR4 Antagonist AMD3100 Modulates Claudin Expression and Intestinal Barrier Function in Experimental Colitis

Ulcerative colitis is a gastrointestinal disorder characterized by local inflammation and impaired epithelial barrier. Previous studies demonstrated that CXC chemokine receptor 4 (CXCR4) antagonists could reduce colonic inflammation and mucosal damage in dextran sulfate sodium (DSS)-induced colitis....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Xia, Xian-Ming, Wang, Fang-Yu, Zhou, Ju, Hu, Kai-Feng, Li, Su-Wen, Zou, Bing-Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207859/
https://ncbi.nlm.nih.gov/pubmed/22073304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027282
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