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The major central endocannabinoid directly acts at GABA(A) receptors

GABA(A) receptors are the major ionotropic inhibitory neurotransmitter receptors. The endocannabinoid system is a lipid signaling network that modulates different brain functions. Here we show a direct molecular interaction between the two systems. The endocannabinoid 2-arachidonoyl glycerol (2-AG)...

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Dettagli Bibliografici
Autori principali: Sigel, Erwin, Baur, Roland, Rácz, Ildiko, Marazzi, Janine, Smart, Trevor G., Zimmer, Andreas, Gertsch, Jürg
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207709/
https://ncbi.nlm.nih.gov/pubmed/22025726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113444108
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