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Mania-like behavior induced by genetic dysfunction of the neuron-specific Na(+),K(+)-ATPase α3 sodium pump

Bipolar disorder is a debilitating psychopathology with unknown etiology. Accumulating evidence suggests the possible involvement of Na(+),K(+)-ATPase dysfunction in the pathophysiology of bipolar disorder. Here we show that Myshkin mice carrying an inactivating mutation in the neuron-specific Na(+)...

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Autors principals: Kirshenbaum, Greer S., Clapcote, Steven J., Duffy, Steven, Burgess, Christian R., Petersen, Janne, Jarowek, Karolina J., Yücel, Yeni H., Cortez, Miguel A., Snead, O. Carter, Vilsen, Bente, Peever, John H., Ralph, Martin R., Roder, John C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207708/
https://ncbi.nlm.nih.gov/pubmed/22025725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108416108
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