Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants

Recent discoveries of hundreds of common susceptibility SNPs from genome-wide association studies provide a unique opportunity to examine population genetic models for complex traits. In this report, we investigate distributions of various population genetic parameters and their interrelationships u...

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Detalhes bibliográficos
Main Authors: Park, Ju-Hyun, Gail, Mitchell H., Weinberg, Clarice R., Carroll, Raymond J., Chung, Charles C., Wang, Zhaoming, Chanock, Stephen J., Fraumeni, Joseph F., Chatterjee, Nilanjan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207674/
https://ncbi.nlm.nih.gov/pubmed/22003128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114759108
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