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Differential Regulation of N-Myc and c-Myc Synthesis, Degradation, and Transcriptional Activity by the Ras/Mitogen-activated Protein Kinase Pathway

Myc transcription factors are important regulators of proliferation and can promote oncogenesis when deregulated. Deregulated Myc expression in cancers can result from MYC gene amplification and translocation but also from alterations in mitogenic signaling pathways that affect Myc levels through bo...

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Bibliografiset tiedot
Päätekijät: Kapeli, Katannya, Hurlin, Peter J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207449/
https://ncbi.nlm.nih.gov/pubmed/21908617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.276675
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